UTSA vs. South Florida odds, line: 2025 college football picks for Week 11 predictions from proven model - SportsLine.com

UTSA vs. South Florida Odds and Predictions for Week 11

The South Florida Bulls aim to remain competitive in the American Athletic Conference championship race as they face the UTSA Roadrunners in a crucial Thursday night matchup.

Team Performance and Records

Offensive and Scoring Trends

Game Details and Betting Lines

The game will kick off at 7:30 p.m. at Raymond James Stadium in Tampa, Florida. The Roadrunners won their only prior meeting in 2023 with a 49-21 victory.

The Bulls enter as 14-point favorites, with the over/under set at 67.5 total points according to SportsLine consensus odds.

Expert Analysis

The model simulates every FBS game 10,000 times, providing precise betting advice for the South Florida picks and college football predictions.

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Author's Summary

This matchup pits a strong home South Florida team against an improving UTSA squad, with the game expected to be high scoring and tightly contested under expert predictions.

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SportsLine SportsLine — 2025-11-06