Heart Health: Long-Term Melatonin Use Linked to Cardiovascular Risk
New research indicates that individuals with insomnia who take melatonin supplements for over a year face an increased risk of heart failure compared to those who do not use this popular sleep aid. The study reveals that long-term melatonin users are more likely to be diagnosed with heart failure, hospitalized for the condition, or experience death from any cause.
This preliminary research will be presented at the American Heart Association’s Scientific Sessions 2025 in New Orleans. However, it has not yet been published in a peer-reviewed scientific journal.
Study Findings and Limitations
- The researchers do not confirm a direct cause-and-effect link between melatonin use and heart failure risk.
- The findings raise safety concerns about prolonged melatonin use.
- Further studies are needed to evaluate the cardiovascular safety of melatonin supplements.
Concerns About Melatonin Supplement Regulation
Many melatonin supplements are available over-the-counter without a prescription. These products are not strictly regulated, allowing people to use them without medical supervision.
“Melatonin supplements may not be as harmless as commonly assumed.”
Author’s Summary
Long-term melatonin use might increase heart failure risk, highlighting the importance of cautious use and further cardiovascular safety research.