A newly developed nanoparticle vaccine has shown strong potential in preventing and treating aggressive cancers in preclinical studies, according to researchers at the University of Massachusetts Amherst.
The experimental approach uses engineered nanoparticles to deliver both immune-stimulating agents and cancer-specific antigens, stopping tumor growth and preventing cancer from spreading in mice.
In one trial, up to 88% of mice that received the vaccine remained free of tumors, depending on the cancer type.
None developed lung metastases when researchers exposed vaccinated mice to cancer cells systemically, mimicking how tumors spread.
Author's summary: Nanoparticle vaccine shows promise in cancer treatment.