NFL picks, predictions: 3 plus-money bets for Week 6

NFL Picks and Predictions for Week 6

The NFL season continues with Week 6, and here are 3 plus-money bets to consider.

By Spenser Davis, published on Oct 12, 2025.

Week 6 Predictions

Last week's NFL bold predictions went 2-1, resulting in a +1.17 unit gain. Since Week 3, the picks in this story have earned 2.16 units.

This Week's Bets

Indianapolis is currently averaging 3.39 points per drive, which would be the highest this century if maintained all season.

Author's summary: NFL Week 6 picks and predictions.

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